NOFO: Innovative Health Practices to Improve Health Outcomes

Grant Size $1,000,000,000   ,   Closing Date


USAID invites organizations and companies to submit an Expression of Interest (EOI) and participate in generating novel tools and approaches that accelerate and sustain improved health outcomes in low-and-middle-income countries (LMICs).

The United States Agency for International Development (USAID) is issuing this Broad Agency Announcement (BAA) to seek participants to co-create, co-design, co-invest, and collaborate on creating, piloting, and scaling innovative research and development interventions utilizing innovative health practices to help reduce disease and mortality rates worldwide.

Problem Statement

The global community has made great strides in reducing mortality around the world over the last 50 years, but progress in developing countries lags far behind that seen in developed countries. Every year an estimated 303,000 women die during pregnancy and childbirth, 5.9 million children die, and an even greater number become infected with life threatening diseases like HIV/AIDS, malaria, diarrhea, pneumonia, and tuberculosis, among others. The vast majority of deaths due to these largely preventable causes occur in developing countries where access to health services is often poor. Outbreaks of emerging infectious diseases like Ebola and Zika only serve to further compound these health challenges, taxing already stressed health systems and elevating the risk of disease epidemics of global proportions.


Harness the power of research and development (R&D), innovation, and innovative practices in health, including science, technology, market-based approaches, and financing, to generate new knowledge, tools, and approaches that can reduce LMIC mortality down to the levels seen in high-income countries (HICs). USAID and its partners will work to identify promising R&D approaches that will help to achieve USAID’s goals of preventing child and maternal deaths, controlling the HIV/AIDS epidemic, and combating infectious diseases. The proposed concepts will be locally-oriented and aim to work in support of, and alongside, populations to find appropriate and lasting solutions to their own health challenges.

Funding Information
  • Award Ceiling: $1,000,000,000

  • Award Floor: $1,000,000,000


Public, private, for-profit, and nonprofit organizations, as well as institutions of higher education, public international organizations, non-governmental organizations, U.S. and non-U.S. governmental organizations, multilateral and international donor organizations are eligible under this BAA. All organizations must be determined to be responsive to the BAA and sufficiently responsible to perform or participate in the final award type.

Post Date: 22-Feb-2023

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